21-day around Italy's boot: Greek isles & Istanbul overnight

Your voyage begins in Civitavecchia (for Rome), Italy. Your gateway to the Eternal City, Civitavecchia has served as Rome's seaport since the 13th century. The port has a long and venerable history. The emperor Trajan built a pleasure villa near the modern city, while Bernini and Michelangelo designed the harbor fortifications.Yet the Eternal City eternally beckons. The ancient capital of the Western World and the center of Christianity for nearly 2,000 years, Rome provides an inexhaustible feast. Visit the ruins of the Forum, view the splendors of the Sistine Chapel, or climb the Spanish Steps, once the heart of Rome's Bohemian Quarter.Rome has been a magnet luring the world's greatest artists, architects, and philosophers since the days of the Caesars.

Italy's third-largest city, Naples is a bustling metropolis famed for it stately buildings, crowded streets, pizza - and notoriously bad traffic. However, this beautiful city is rich in centuries-old culture and customs. Naples is also your gateway to the Isle of Capri, the fabled Amalfi Coast and the ruins of Pompeii, buried in ash by the cataclysmic eruption of Mt. Vesuvius in 79 A.D. Naples boasts an ideal location, with both the ruins of Roman cities and the stunning Amalfi Coast in easy reach.

Your ship calls at Messina, Italy.

Your ship calls at Cruising Strait of Messina.

Malta is the largest in a group of seven islands that occupy a strategic position between Europe and Africa. The island's history is long and turbulent. Everyone from the Normans to the Nazis have vied for control of this small, honey-colored rock. For centuries the island was the possession of the knightly Order of St. John - the Knights Hospitaller. Valletta, Malta's current capital, was planned by the Order's Grandmaster Jean de la Valette to secure the island's eastern coast from Turk incursions. Founded in 1566, Valletta's bustling streets are lined with superb Baroque buildings and churches.Malta has a long history: the megalithic stone temples at Gozo may be the oldest freestanding structures on Earth. Malta has two official languages, Maltese (constitutionally the national language) and English. Malta was admitted to the European Union in 2004 and in 2008 became part of the eurozone.

A full day at sea - time to enjoy Nieuw Amsterdam's restaurants, pools and entertainment.

Your ship calls at Zakinthos, Greece.

The lush and verdant island of Corfu lies in the Ionian Sea, midway between Greece and Italy. The island has a long and colorful history. First colonized by the city-state of Corinth, Corfu has been ruled by the Romans, the Venetians, the French and the English. Corfu Town boasts fortresses bearing the insignia of the Venetian Republic, an esplanade lavishly planted by the French during the Napoleonic Wars, and an English cricket pitch. The island also offers some of the finest coastal scenery in the entire Mediterranean.Corfu's old town is a mixture of the medieval and the modern. The Esplanade, planted with palms and eucalyptus by the French, leads to the English cricket pitch.

Your ship calls at Scenic cruising Bay of Kotor.

Kotor lies at the head of Boka Bay. Bordered by towering limestone cliffs, the winding bay is actually Southern Europe's longest and most dramatic fjord. The port itself is a medieval gem: its narrow, asymmetrical streets are lined with ancient stone houses, old palaces, and churches dating from the 12th century. Kotor is also your gateway to the cultural and scenic wonders of Montenegro, from the old royal capital at Cetinje to the marshes and wildlife of Lake Skadar National Park.Kotor is renowned for its nightlife: the streets of the old port are lined with pubs, taverns and cafés. The city is also host to a renowned summer carnival.Kotor is an anchorage port. Passengers transfer to shore via ship's tender.

Dubrovnik is a beautiful stone jewel hugging the Adriatic Sea. This picture-perfect medieval walled city offers ancient stone buildings, narrow cobbled streets and fortified ramparts rising above red-tiled rooftops. Stradun is the city's focal point and main artery while Dubrovnik's streets are blessedly free of vehicular traffic. Despite the heavy damage inflicted by shelling in the early '90s, Dubrovnik has been restored to its pre-war beauty. A UNESCO World Heritage Site, the old city remains the pride of the Republic of Croatia.For six centuries Dubrovnik was an independent republic - an oligarchy ruled by patrician families. The Republic was overthrown by Napoleon in 1808.Note: All passengers must carry an original photo I.D. when going ashore: photocopies are not accepted.On occasion, Dubrovnik will be an anchorage port; passengers transfer to shore via ship's tender.

Pine-clad hills, secluded coves, beaches - Split and the Dalmatian Riviera have been premier destinations on the Adriatic since the days of the Roman emperors. In fact, medieval Split was built within and around the palace complex built for the emperor Diocletian in his retirement. (The complex included both a villa and a castrum - a Roman camp capable of garrisoning three legions!) The charms that soothed an emperor are still evident today. The Dalmatian Riviera offers the traveler a heady blend of natural beauty and fascinating cultural sites.Diocletian abdicated in 305 A.D. During his reign, the emperor ruthlessly persecuted Christians. Ironically Split's St Dominius' Cathedral occupies his mausoleum.

Continue your voyage aboard Nieuw Amsterdam with a leisurely day at sea.

Tucked in the country's northeast corner on the Adriatic Sea and once the flourishing port of the Austro-Hungarian Empire, Trieste became a largely forgotten borderland after World War I. But today, those who visit find a blend of cultures and languages of Europe, with a rich literary legacy - a city that's lured great authors from Ranier Maria Rilke to James Joyce. Waves from the Adriatic lap its elegant promenades. It lies below the Karst, limestone cliffs that are a popular destination for nature lovers and where vineyards produce wines that taste of sea and stone. Legend has it Jason and the Argonauts - with the golden fleece - sailed in from an underground river. A well-preserved Roman theater, that once seated up to 6,000 spectators, is testimony that in antiquity, this was a thriving city. Gilded mosaics in San Giusto Cathedral are evidence of Byzantine influence. Trieste offers endless opportunity for exploration not only in the town and surroundings, but also to neighboring Slovenia and not so far distant Venice.

Is the oldest continuously inhabited city in Croatia. It is situated on the Adriatic Sea, at the northwestern part of Ravni Kotari region.

Your ship returns to Dubrovnik, Croatia.

Another day at sea to explore the ship at your own pace.

Did the catastrophic volcanic eruption that ravaged Santorini circa 1600 B.C. destroy Crete's ancient Minoan civilization - and give birth to the myth of Atlantis? In 1967, archaeologists on Santorini unearthed the remains of a Bronze Age city that may have been home to as many as 30,000 people. Whether the Lost Continent of Atlantis is rooted in myth or reality, an undisputed fact remains. The eruption created a caldera - and one of the most dramatic land and seascapes in the entire Mediterranean. On Santorini, whitewashed buildings cling to vertiginous cliffs that plunge to a turquoise sea. Part of the Cyclades Archipelago, the three-island group of Santorini, Thirasia and uninhabited Aspronisi present the traveler with unforgettable vistas.The island has had a number of names throughout history - from Strongyle or "Round" to Thera in honor of an ancient hero. Santorini is more recent and stems from the island church dedicated to St. Irene - Santa Rini to foreign sailors.Note: Santorini is an anchorage port: passengers transfer to shore via shore tender.

Thanks to its proximity to the mainland, Mykonos was one of the first Greek islands to become an international travel destination. During the late '60s and early '70s, Mykonos was famed as a haunt for the rich. The island's nightlife - then and now - was a glittering whirl of colored lights, music, and parties. But there's another side to Mykonos - the neighboring island of Delos. In classical mythology, Delos was the birthplace of Apollo and his twin sister Artemis. Travelers to Delos can stroll among the island's vast ruins, which include three temples consecrated to the Sun God and the famed Lions Walk.Mykonos town features hip boutiques, restaurants, jewelry stores, souvenirs, taverns and cafés. The island's famed windmills are found just south of the waterfront.

From the port of Kusadasi on Turkey's Anatolian Coast, one travels into the past. Nearby stand the ruins of ancient Ephesus, a major site of archeological excavation. The city was once a Roman provincial capital and trading center. Ephesus is also home to several of Christendom's holiest sites. St. Paul preached at the Great Theater and the ruins of Ephesus' Basilica cover the tomb of Christ's most beloved disciple, St. John the Apostle.In Kusadasi, whitewashed stone houses rise in tiers behind the market district. The palm-lined esplanade is the center of town life, with thousands of merchants offering wares to rival the Grand Bazaar in Istanbul.

Your ship calls at Cruising The Dardanelles.

Istanbul rises from the Bosphorus, a vision of minarets and domes sparkling in the light. The capital of vanished empires, Istanbul is a true crossroad, the only city on Earth to span two continents. This meeting place of Europe and Asia, of Christian and Muslim, is one of the great adventures a traveler encounters. Browse the stalls of the world's largest bazaar, explore ancient mosques and churches, and gaze at the stunning jewels in the Topkapi Palace.Istanbul has dominated the Straits of Bosphorus for 25 centuries. As Constantinople, capital of the Eastern Roman Empire, it was a metropolis of stunning splendor when the great cities of Europe were mere villages.

A second day in Istanbul, Turkey - time to explore at your own pace.

A full day at sea - time to enjoy Nieuw Amsterdam's restaurants, pools and entertainment.

The past maintains a vibrant presence in the cradle of Western civilization. Atop the Acropolis, the serene Parthenon sails above the commotion of the modern city. The tragedies of Aeschylus, Sophocles, and Euripides were performed in the Theater of Dionysus at the foot of the Acropolis. On Pnyx Hill, citizens of a fledgling democracy gathered to cast their votes on Athens' destiny. Then there is the hustle and bustle of the modern city, a metropolis of 4.5 million that spreads out from the foot of Mt. Lycabettus and across the plain. Packed with busy shops and lively tavernas, modern Athens is a colorful counterpoint to classical Greece. Piraeus is the port city for Athens and has been Athens' port of entry for over two millennia.