21-day Greek isles: Egypt, holy land & Istanbul overnight

Your voyage begins in Athens (Piraeus), Greece. The past maintains a vibrant presence in the cradle of Western civilization. Atop the Acropolis, the serene Parthenon sails above the commotion of the modern city. The tragedies of Aeschylus, Sophocles, and Euripides were performed in the Theater of Dionysus at the foot of the Acropolis. On Pnyx Hill, citizens of a fledgling democracy gathered to cast their votes on Athens' destiny. Then there is the hustle and bustle of the modern city, a metropolis of 4.5 million that spreads out from the foot of Mt. Lycabettus and across the plain. Packed with busy shops and lively tavernas, modern Athens is a colorful counterpoint to classical Greece. Piraeus is the port city for Athens and has been Athens' port of entry for over two millennia.

A full day at sea - time to enjoy Nieuw Amsterdam's restaurants, pools and entertainment.

Your ship calls at Alexandria (Cairo), Egypt.

Continue your voyage aboard Nieuw Amsterdam with a leisurely day at sea.

Your ship calls at Haifa (Tel Aviv), Israel.

Your ship calls at Ashdod (Jerusalem), Israel.

Your ship calls at Limassol, Cyprus.

Your ship calls at Antalya, Turkey.

Another day at sea to explore the ship at your own pace.

Your ship calls at Bodrum, Turkey.

Thanks to its proximity to the mainland, Mykonos was one of the first Greek islands to become an international travel destination. During the late '60s and early '70s, Mykonos was famed as a haunt for the rich. The island's nightlife - then and now - was a glittering whirl of colored lights, music, and parties. But there's another side to Mykonos - the neighboring island of Delos. In classical mythology, Delos was the birthplace of Apollo and his twin sister Artemis. Travelers to Delos can stroll among the island's vast ruins, which include three temples consecrated to the Sun God and the famed Lions Walk.Mykonos town features hip boutiques, restaurants, jewelry stores, souvenirs, taverns and cafés. The island's famed windmills are found just south of the waterfront.

Your ship returns to Athens (Piraeus), Greece.

Your ship returns to Mykonos, Greece.

A full day at sea - time to enjoy Nieuw Amsterdam's restaurants, pools and entertainment.

Istanbul rises from the Bosphorus, a vision of minarets and domes sparkling in the light. The capital of vanished empires, Istanbul is a true crossroad, the only city on Earth to span two continents. This meeting place of Europe and Asia, of Christian and Muslim, is one of the great adventures a traveler encounters. Browse the stalls of the world's largest bazaar, explore ancient mosques and churches, and gaze at the stunning jewels in the Topkapi Palace.Istanbul has dominated the Straits of Bosphorus for 25 centuries. As Constantinople, capital of the Eastern Roman Empire, it was a metropolis of stunning splendor when the great cities of Europe were mere villages.

A second day in Istanbul, Turkey - time to explore at your own pace.

Continue your voyage aboard Nieuw Amsterdam with a leisurely day at sea.

From the port of Kusadasi on Turkey's Anatolian Coast, one travels into the past. Nearby stand the ruins of ancient Ephesus, a major site of archeological excavation. The city was once a Roman provincial capital and trading center. Ephesus is also home to several of Christendom's holiest sites. St. Paul preached at the Great Theater and the ruins of Ephesus' Basilica cover the tomb of Christ's most beloved disciple, St. John the Apostle.In Kusadasi, whitewashed stone houses rise in tiers behind the market district. The palm-lined esplanade is the center of town life, with thousands of merchants offering wares to rival the Grand Bazaar in Istanbul.

Your ship calls at Kos, Greece.

The largest and arguably the most beautiful of the 12 islands forming the Dodecanese, Rhodes has long played a major role in history. Lying just 12 miles off the coast of Turkey, the island straddles the sea-lanes linking Egypt, Southern Europe and the Holy Land. Rhodes Town bears witness to that long history. The ancient city features a classical stadium and the ruins of the Temple of Apollo. The "old" city is a walled town with medieval buildings and streets harking back to the days of the Crusades. The new town is a Mecca of luxury resorts lining the island's picturesque Mandaraki Harbor.The Colossus of Rhodes, one of the Seven Wonders of the Ancient World, is reputed to have once stood guard over the harbor. Today, the bronze statues of a stag and doe top the two columns marking the harbor entrance.

Another day at sea to explore the ship at your own pace.

Your voyage concludes in Athens (Piraeus), Greece.